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Diverticula Disease |
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Diverticular disease results in mucosal
outpouches in the distal colon.
Diverticular disease causes herniation of the mucosa of the colon through the
muscularis
propria, producing outpouches of the bowel lumen.
There is thickening of the muscularis propria.
Complications are related to stagnation of contents of the diverticulae, with
secondary
inflammation. Acute diverticulitis is the result of acute inflammation of a
diverticulum.
Haemorrhage may result or the diverticulum may rupture, leading to peritonitis
or the
development of a paracolic abscess.
Chronic inflammation may occur, with walling off of an area of inflammation by
fibrous tissue.
The resulting scarring and inflammatory changes form a diverticular mass, which
may cause large bowel obstruction and may mimic the appearances of a carcinoma
of the colon on imaging.
Melanosis coli is associated with chronic laxative use
Patients who take laxatives for constipation sometimes develop black coloration
of the
mucosa of the large bowel, termed 'melanosis coli'.
Histologically this is seen as accumulation of pigment-laden macrophages in the
lamina propria of the colon. |
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We give here simplified and accurate information about the disease
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